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Literature summary extracted from

  • Lin, J.; Fu, W.; Cen, P.
    Characterization of 5-aminolevulinate synthase from Agrobacterium radiobacter, screening new inhibitors for 5-aminolevulinate dehydratase from Escherichia coli and their potential use for high 5-aminolevulinate production (2009), Biores. Technol., 100, 2293-2297.
    View publication on PubMed

Application

EC Number Application Comment Organism
2.3.1.37 synthesis by expression in Escherichia coli Rosetta and combining D-xylose as a inhibitor for 5-aminolevulinate dehydratase with D-glucose in fed-batch culture and based on the optimal culture system, the yield of 5-aminolevulinate achieved is 7.3 g/l or 56 mM under the appropriate conditions Agrobacterium tumefaciens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.37 expression in Escherichia coli Agrobacterium tumefaciens
4.2.1.24 His-tagged Escherichia coli

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.37 additional information not inhibitory: D-glucose, D-fructose, D-xylose, D-mannose, L-arabinose, D-galactose, lactose, sucrose and maltose Agrobacterium tumefaciens
4.2.1.24 D-glucose
-
 Escherichia coli
4.2.1.24 D-xylose
-
 Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.37 Agrobacterium tumefaciens
-
-
-
4.2.1.24 Escherichia coli
-
 Rosetta(DE3)
-
4.2.1.24 Escherichia coli Rosetta(DE3)
-
 Rosetta(DE3)
-

Synonyms

EC Number Synonyms Comment Organism
4.2.1.24 5-aminolevulinate dehydratase
-
 Escherichia coli